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Last update: 09 May 2017
 
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News
Joining ERA-IB consortium MetaCat [January 2017]
Since January 2017 our department belongs to the MetaCat consortium - a metagenomic collection of novel and highly efficient biocatalysts for industrial biotechnology (→ read more)
New OBAC cluster funded within ERA-IB [November 2016]
Partners form Frankfurt, Ulm, La Coruna, Gent and Göttingen will work together within the joint project 'OBAC - Overcoming energetic barriers in acetogenic conversion of carbon dioxide'. (→ read more)
FLEXIZUCKER - new BMEL funded project [October 2016]
Process engineering, enzymatic and genomic characterization of a flexible biogas production with targeted use of sugar beets (→ read more)
Annual Genomics Workshop [July 2016]
The 4th 'International Workshop on Prokaryotic Genomics & Bioinformatics' took place from 19-22 July 2016. (→ read more)
CDiff project elongation until 2018 [July 2016]
A research co-operation of microbiologists from northern Germany analyses the hospital-aquired pathogen Clostridium difficile in order to develop new diagnostic tools and therapies. (→ read more)
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Göttingen Genomics Laboratory

Logo Microbial genome analysis provides an important research paradigm in the fields of microbiology, molecular genetics, biotechnology and infectious disease biology. Göttingen Genomics Laboratory (G2L) is a major centre of activities in these areas within Germany. G2L was founded in 1997 by Hans-Joachim Fritz and Gerhard Gottschalk with financial support from the Ministry of Science and Culture of Lower Saxony. Chairman of the lab is Rolf Daniel.

Göttingen Genomics Laboratory is an internationally renowned centre for the sequencing and annotation of microbial genomes and metagenomes. Its work also covers the processing of sequence data used for functional genome analysis. Methods for determining the size of microbial genomes, for producing plasmid libraries with defined insert sizes and for generating cosmid, fosmid and cDNA libraries are as similarly well established as is high-throughput microbial genome sequencing.
Strategies and the corresponding bioinformatical tools are available to effectively assemble and edit sequencing data and close sequence gaps. The centre's performance is documented in numerous publications in high-impact journals. The G2L maintains a database on all sequenced microbial genomes. This database also facilitates the annotation of sequenced genomes and, specifically, enables their metabolic reconstruction and comparative genome analysis.
An additional facility is the transcriptome laboratory where genome-wide DNA microarrays are produced; these microarrays can be used for physiological assays and in continuous cultures. Such experiments are supplemented by meta-transcriptome analyses based on the sequencing of cDNA obtained from microbial RNA.
G2L plays a pivotal role in various sequencing projects of BMBF/BMELV/DFG funded research networks, and it is a centre of cooperations with external research groups.

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