› Home  › News  › Archive
Last update: 04 Aug 2017
 
logo
Workshop on Genomics & Bioinformatics [July 2017]
The 5th 'International Workshop on Prokaryotic Genomics & Bioinformatics' took place from 18-21 July 2017 (→ read more)
Joining ERA-IB consortium MetaCat [January 2017]
Since January 2017 our department belongs to the MetaCat consortium - a metagenomic collection of novel and highly efficient biocatalysts for industrial biotechnology (→ read more)
New OBAC cluster funded within ERA-IB [November 2016]
Partners form Frankfurt, Ulm, La Coruna, Gent and Göttingen will work together within the joint project 'OBAC - Overcoming energetic barriers in acetogenic conversion of carbon dioxide'. (→ read more)
FLEXIZUCKER - new BMEL funded project [October 2016]
Process engineering, enzymatic and genomic characterization of a flexible biogas production with targeted use of sugar beets (→ read more)
Annual Genomics Workshop [July 2016]
The 4th 'International Workshop on Prokaryotic Genomics & Bioinformatics' took place from 19-22 July 2016. (→ read more)
arrowUp

News (Archive)

› Annual Genomics Workshop [July 2016] (→ read more)
› CDiff project elongation until 2018 [July 2016] (→ read more)
› ANTIRES - new joint project [June 2016] (→ read more)
› ProkaGENOMICS 2015 conference [Oct 2015] (→ read more)
› iGEM Team Göttingen 2015 [September 2015] (→ read more)
› Annual Genomics Workshop [July 2015] (→ read more)
› RETROBIO - Successful project application within ERASynBio [March 2015] (→ read more)
› Annual Genomics Workshop [July 2014] (→ read more)
› BEFmate - new joint project [March 2014] (→ read more)
› 'Roseobacter'-SFB verlängert [November 2013] (→ read more)
› Norddeutscher Wissenschaftspreis 2013 verliehen [November 2013] (→ read more)
› Annual Genomics Workshop [October 2013] (→ read more)
› CDiff: Start of 3.9 Million Euro project [August 2013] (→ read more)
› ERA-IB 3 consortium has started work [May 2013] (→ read more)
› Forschungsprojekt: Europäische Faulbrut bei Bienen [4. April 2013] (→ read more)
› Ministerin Wanka eröffnet neues Genomik-Zentrum [11. Januar 2013] (→ read more)
› New multilateral research project within ERA-IB [December 2012] (→ read more)
› New DFG Priority Programme: Ecosystem Nutrition [May 2012] (→ read more)
› Next Polarstern trip started in March (Puntas Arenas, Chile) [March 2012] (→ read more)
› SFB 990 (Sumatra) started / Project B02 [January 2012] (→ read more)
› Two Co-Workers left for Polarstern trip (Cape Town, South Africa) [December 2011] (→ read more)
› Not EHEC, but rather EAHEC [June 2011] (→ read more)

RETROBIO - Successful project application within ERASynBio (March 2015)
Partners form Zürich, Basel, Göttingen and Graz will work together within the joint project 'RETROBIO - A twofold retrosynthetic implementation of a novel biochemical pathway'.
The 1st joint call for proposals of ERASynBio was launched in May 2013 under the ERA-NET Scheme of the Seventh Framework Programme (FP7) of the European Commission. The call for proposals resulted in 55 proposals. After the assessment of an international Expert Evaluation Panel, the ERASynBio Call Group has selected 8 projects for funding.

RETROBIO Partners:
ETH Zürich - Prof. Sven Panke (Co-ordinator)
University of Basel - Prof. Florian Seebeck
University of Göttingen - Prof. Rolf Daniel
Graz University of Technology - Prof. Rolf Breinbauer

Project description:
We retrosynthetically designed a pathway along a completely novel set of new-to-nature metabolites for the synthesis of biotin, a high-value-added commercially relevant product currently manufactured by a chemical synthesis. The pathway will be implemented using rational design approaches complemented by advanced high throughput screening methods for the reprogramming of the substrate specificities of known enzymes. The project aims to demonstrate that multi-step biopathway design largely outside of the scope of reactions already known in nature is possible and provides attractive solutions to some of synthetic biology’s currently most intractable synthetic problems. Furthermore, we will demonstrate experimentally that retrosynthetic design is an excellent basis for rational biopathway design.
We expect the results to be a milestone in the demonstration of the potential of synthetic biology for the development of chemical syntheses, which hopefully encourages the more frequent application of biosynthesis as an alternative to chemical methods.